• Circ 03955 promotes pancreatic cancer tumorigenesis and Warburg effect by targeting the miR-3662/HIF-1α axis

    2 monthes ago - By Springer

    Abstract
    Objectives
    Former studies found that circRNAs play an important part in the occurrence of a variety of malignant biological characteristics that are critical for cancer progression. It has been shown that circ 03955 is highly expressed and implicated with quantities of biological processes in solid tumor. However, whether circ 03955 regulates the tumorigenesis and Warburg effect of pancreatic cancer remains largely unknown.
    Materials and methods
    The level of circ 03955 in PC tissues and cell lines was determined by real-time qPCR. Loss-of-function and gain-of-function assays were...
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