• Discovery of a transcriptomic core of genes shared in 8 primary retinoblastoma with a novel detection score analysis

    15 days ago - By Springer

    Abstract
    Purpose
    Expression microarrays are powerful technology that allows large-scale analysis of RNA profiles in a tissue; these platforms include underexploited detection scores outputs. We developed an algorithm using the detection score, to generate a detection profile of shared elements in retinoblastoma as well as to determine its transcriptomic size and structure.
    Methods
    We analyzed eight briefly cultured primary retinoblastomas with the Human transcriptome array 2.0. Transcripts and genes detection scores were determined using the Detection Above Background algorithm. We used...
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