• Comprehensive analysis of the HOXA gene family identifies HOXA13 as a novel oncogenic gene in kidney renal clear cell carcinoma

    15 days ago - By Springer

    Abstract
    Objectives
    Kidney renal clear cell carcinoma is one of the most common lethal cancers in the human urogenital system. As members of the Homeobox family, Homeobox-A cluster genes have been reported to be involved in the development of many cancer types. However, the expression and clinical significance of HOXA genes in KIRC remain largely unknown.
    Materials and methods
    In this study, we comprehensively analyzed the mRNA expression and prognostic values of HOXA genes in KIRC using The Cancer Genome Atlas analysis databases online. Colony formation assay, flow cytometry and Western...
    Read more ...