• Eagle: multi-locus association mapping on a genome-wide scale made routine

    8 days ago - By Oxford Journals

    AbstractMotivationWe present Eagle, a new method for multi-locus association mapping. The motivation for developing Eagle was to make multi-locus association mapping "easy" and the method-of-choice. Eagle's strengths are that it a. is considerably more powerful than single-locus association mapping b. does not suffer from multiple testing issues c. gives results that are immediately interpretable and d. has a computational footprint comparable to single-locus association mapping.ResultsBy conducting a large simulation study, we will show that Eagle finds true and avoids false SNP-trait...
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