BioTech Mag Search: Protein
Predicting cryptic ligand binding sites based on normal modes guided conformational sampling
Abstract To greatly expand the druggable genome, fast and accurate predictions of cryptic sites for small molecules binding in target proteins are in high demand. In this...
9 hours ago - Wiley
Effects of Amino Acid Modifications on the Permeability of the Pentameric Sarcolipin Channel
Abstract Sarcolipin is an important transmembrane protein encoded by long noncoding RNA. SLN is expressed in the sarcoplasmic reticulum and regulates cardiac and skeletal...
9 hours ago - Wiley
ISLAND: in-silico proteins binding affinity prediction using sequence information
Determining binding affinity in protein-protein interactions is important in the discovery and design of novel therapeutics and mutagenesis studies. Determination of binding...
16 hours ago - BioData Mining
Crystal structure of PYCH 01220 from Pyrococcus yayanosii potentially involved in binding nucleic acid
Abstract We report the crystal structure of PYCH 01220, a hypothetical protein in Pyrococcus yayanosii CH1. This protein is composed of two domains, named Domain A and Domain...
1 day ago - Wiley
Senior Scientist - Protein Biochemist - Quidel Corporation - San Diego, CA
Quidel Corporation is a leading manufacturer of diagnostic healthcare solutions serving to enhance the health and wellbeing of people around the globe with well...From Quidel...
1 day ago - San Diego Biotechnology - 3 articles
Sr. Manager, Analytical Development - Emergent Biosolutions - San Diego, CA
Minimum of 5 years' experience managing a team. Provide leadership and technical direction to the protein characterization group for development and execution...From Emergent...
1 day ago - San Diego Biotechnology - 2 articles
Scientists discover a motif that guides assembly of the algal pyrenoid
Researchers have discovered that assembly of the algal pyrenoid, a structure that mediates the incorporation of carbon dioxide into sugars, is guided by the presence of a...
1 day ago - ScienceDaily - 2 articles
Insights into amphicarpy from the compact genome of the legume Amphicarpaea edgeworthii
Abstract Amphicarpy is a unique and fascinating reproductive strategy wherein a single plant produces both aerial and subterranean fruits. This strategy is believed to be an...
2 days ago - Wiley
Jeffrey Hatfield takes over from Diego Miralles as CEO of Vividion; Dragonfly scores a new exec with COO Alex Lugovskoy
Jeffrey Hatfield ? San Diego protein degradation startup Vividion Therapeutics has made a change at the top with Jeffrey Hatfield taking the helm as CEO, replacing Diego...
2 days ago - San Diego Biotechnology
Ambrx, Inc.: Senior Accountant
Ambrx, Inc.: Ambrx is a clinical-stage biopharmaceutical company with a mission to deliver breakthrough protein therapeutics through our proprietary technology inc La Jolla...
2 days ago - San Diego Biotechnology
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Better Apple Pies: HiFi Reads are a Perfect Recipe...
Zhangjun Fei inspects a Mutsu apple at Indian Creek Farm in Ithaca, NY. Image credit: Boyce Thompson Institute Scientists at the Boyce Thompson Institute, Cornell University...
Metabolic engineering of Saccharomyces cerevisiae for high-level production...
The natural phenolic glycoside gastrodin is the major bioactive ingredient in the well-known Chinese herb Tianma and is widely used as a neuroprotective medicine in the clinic...
Dual and mutual interaction between microbiota and viral infections: a...
All of humans and other mammalian species are colonized by some types of microorganisms such as bacteria, archaea, unicellular eukaryotes like fungi and protozoa, multicellular...
Efficient protection of microorganisms for delivery to the intestinal tract...
Gut microbiota in humans and animals play an important role in health, aiding in digestion, regulation of the immune system and protection against pathogens. Changes or...
New plant-based gel to fast-track 'mini-organs' growth, improve cancer treatment
Researchers have created the world's first bioactive plant-based nanocellulose hydrogel to support organoid growth for biomedical applications. This includes cancer development...
Scientists develop new gene therapy for eye disease
Scientists have developed a new gene therapy approach that offers promise for one day treating an eye disease that leads to a progressive loss of vision and affects thousands...
Improving biomedical named entity recognition with syntactic information
Biomedical named entity recognition is an important task for understanding biomedical texts, which can be challenging due to the lack of large-scale labeled training data and...
Special Issue on Ophthalmic Image Analysis and Informatics
In this issue, vol. 24, issue 12, December 2020, 17 papers are published related to the Special Issue on Ophthalmic Image Analysis and Informatics.
Spatially Aware Dense-LinkNet Based Regression Improves Fluorescent Cell...
Recent advancements in ophthalmic imaging technology, based on adaptive optics , have enabled fluorescence imaging of retinal pigment epithelial cells directly inside the...
Effects of Amino Acid Modifications on the Permeability of the Pentameric...
Abstract Sarcolipin is an important transmembrane protein encoded by long noncoding RNA. SLN is expressed in the sarcoplasmic reticulum and regulates cardiac and skeletal...