BioTech Mag Search: Protein
On the Molecular Mechanisms of the Effect of a Zero Magnetic Field on the Production of Reactive Oxygen Species in Inactivated Neutrophils
Abstract -It is shown that the lower intensity of 2,7-dichlorodihydrofluorescein oxidation processes in inactivated neutrophils exposed to hypomagnetic field is not related to...
13 minutes ago - Springer
Plexium Debuts With $28M and a New Take on Protein Degradation Drugs
Even as researchers discover more links between specific proteins and human disease, it's still hard to find small molecules or antibodies that can bind to those drug targets...
43 minutes ago - San Diego Biotechnology
Patch-DCA: Improved Protein Interface Prediction by utilizing Structural Information and Clustering DCA scores
AbstractMotivationOver the past decade there have been impressive advances in determining the 3D structures of protein complexes. However, there are still many complexes with...
3 hours ago - Oxford Journals
San Diego upstart debuts discovery engine that puts a twist to protein degradation
For years, the idea of protein degradation - utilizing the cell's natural garbage disposal system to mark problematic proteins for destruction - remained an elegant but...
5 hours ago - San Diego Biotechnology
Protein Adaptation to High Hydrostatic Pressure: Computational Analysis of the Structural Proteome
ABSTRACT Hydrostatic pressure has a vital role in the biological adaptation of the piezophiles, organisms that live under high hydrostatic pressure. However, the mechanisms by...
13 hours ago - Wiley
Combination of light-driven co-delivery of chemodrugs and plasmonic-induced heat for cancer therapeutics using hybrid protein nanocapsules
Improving the water solubility of hydrophobic drugs, increasing their accumulation in tumor tissue and allowing their simultaneous action by different pathways are essential...
18 hours ago - Journal of Nanobiotechnology
Soybean plants expressing the Bacillus thuringiensis cry8-like gene show resistance to Holotrichia parallela
Cry8-like from Bacillus thuringiensis encodes an insecticidal crystal protein. Holotrichia parallela , commonly known as the dark black chafer, is a troublesome pest of soybe...
20 hours ago - BMC Biotechnology
Yeast surface display of full‐length human microtubule‐associated protein tau
Abstract Microtubule‐associated protein tau is an intrinsically disordered, highly soluble protein found primarily in neurons. Under normal conditions, tau regulates the...
1 day ago - Wiley
Interest of locally weighted regression to overcome nonlinear effects during in situ NIR monitoring of CHO cell culture parameters and antibody glycosylation
Abstract Animal cell culture processes have become the standard platform to produce therapeutic proteins such as recombinant monoclonal antibodies. Since the mAb quality could...
1 day ago - Wiley
Clearance of solvents and small molecule impurities in antibody drug conjugates via ultrafiltration and diafiltration operation
Abstract Ultrafiltration and diafiltration processes by tangential flow filtration are frequently used for removal of solvents and small molecule impurities and for buffer...
1 day ago - Wiley
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Healx Bags $56M to Advance Affordable, AI-Based Orphan Drugs
Atomico, a European venture capital firm, has helped persuade Cambridge, UK-based Healx to return to the capital market a year earlier than anticipated. The biotech has just...
ArsenalBio Launches With $85M for “Programmable” T Cell Therapies
Cell therapies are made by tinkering with a patient's immune cells so that they can better recognize and destroy cancer cells. These drugs give patients another treatment...
Regulating a balance between protection and growth
By Danielle Pycior | Bond LSC It's a sensitive balance between growth and defense when it comes to plants. While a built-in, passive immune system helps them survive attackers...
Nuance & Microsoft Team Up on Conversational AI for Doctors' Offices
Nuance Communications' plan to lighten the clerical burden on physicians is coming into focus, and it involves an assist from tech giant Microsoft. Nuance , the 27-year-old...
Homegrown researcher
Years at MU lands student turned faculty tenure-track position Maggie Lange-Osborn is a newly appointed assistant professor in the Department of Molecular Microbiology and...
Barbara Jacak Receives 2019 Distinguished Scientist Fellow Award
Barbara Jacak Barbara Jacak, director of Lawrence Berkeley National Laboratory's Nuclear Science Division since 2015, has been named a 2019 Distinguished Scientist Fellow by...
New BIO One-on-One Partnering Mobile App
BIO has released a new and improved mobile app for the BIO One-on-One Partnering™ system. After intensive surveys and interviews with attendees who have engaged in partnering...
Eli Lilly Drug Acquired in Armo Deal Fails Pancreatic Cancer Test
An experimental drug that was the centerpiece of a $1.6 billion Eli Lilly acquisition last year has now failed a pivotal test in pancreatic cancer. Eli Lilly said Wednesday...
Alexion to Buy Achillion in $930M Marriage of Rare Disease Drug Firms
Alexion Pharmaceuticals is acquiring Achillion Pharmaceuticals for $930 million, a deal that could strengthen its position providing treatments for a rare blood disorder...
Led by Gilead Veteran Riva, Glenmark's Ichnos Steps Out on Its Own
Glenmark Pharmaceuticals, which has made generic drugs for about four decades, on Tuesday formally spun off its drug R&D unit as an independent business aiming to advance a...