Molecular Targets for the Testing of COVID‐19
RNA and proteins of a Betacoronavirus virion as well as virus induced antibodies can be used as molecular biomarkers for viral infection. This paper describes the principle of...
3 hours ago - Wiley
The Effect of Container Surface Passivation on Aggregation of Intravenous Immunoglobulin Induced by Mechanical Shock
Aggregation of therapeutic proteins can result from a number of stress conditions encountered during their manufacture, transportation, and storage. This work shows the effects...
3 hours ago - Wiley
Homology-dependent recombination of large synthetic pathways into E. coli genome via λ-Red and CRISPR/Cas9 dependent selection methodology
Metabolic engineering frequently needs genomic integration of many heterologous genes for biosynthetic pathway assembly. Despite great progresses in genome editing for the...
7 hours ago - Microbial Cell Factories
Data-based RNA-seq simulations by binomial thinning
With the explosion in the number of methods designed to analyze bulk and single-cell RNA-seq data, there is a growing need for approaches that assess and compare these methods...
7 hours ago - BMC Bioinformatics
A novel investigation of the effect of iterations in sliding semi-landmarks for 3D human facial images
Landmark-based approaches of two- or three-dimensional coordinates are the most widely used in geometric morphometrics. As human face hosts the organs that act as the central...
7 hours ago - BMC Bioinformatics
Substitution matrix based color schemes for sequence alignment visualization
Visualization of multiple sequence alignments often includes colored symbols, usually characters encoding amino acids, according to some properties, such as hydrophobicity or...
7 hours ago - BMC Bioinformatics
RintC: fast and accuracy-aware decomposition of distributions of RNA secondary structures with extended logsumexp
Analysis of secondary structures is essential for understanding the functions of RNAs. Because RNA molecules thermally fluctuate, it is necessary to analyze the probability...
7 hours ago - BMC Bioinformatics
Bio-semantic relation extraction with attention-based external knowledge reinforcement
Semantic resources such as knowledge bases contains high-quality-structured knowledge and therefore require significant effort from domain experts. Using the resources to...
7 hours ago - BMC Bioinformatics
Head, Safety, Security, Health & Environment, Oceanside, CA - GENENTECH - Oceanside, CA
Reporting to the VP & General Manager of Oceanside you will be a member of the Oceanside leadership team and a member of the extended Pharma Technical...From Genentech - Sun...
14 hours ago - San Diego Biotechnology
Multicopper oxidases: modular structure, sequence space and evolutionary relationships
Abstract Multicopper oxidases use copper ions as cofactors to oxidize a variety of substrates while reducing oxygen to water. MCOs have been identified in various taxa, with...
14 hours ago - Wiley
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Importancia de la prueba de anticuerpos para afrontar la COVID-19
Si el mundo algo ha aprendido durante el transcurso de la pandemia de la COVID-19, es la importancia de las pruebas para esta enfermedad. Tener la capacidad de saber quién...
Bone‐Inspired Tube Filling Decellularized Matrix of Toad Cartilage Provided...
Because of its rich cartilage‐like matrix and low immunogenicity, the decellularized toad bone matrix is processed as hydrogel. Mesenchymal stem cells in dBECM hydrogel are...
Crystal Contact Engineering Enables Efficient Capture and Purification of an...
The crystallization of an industrial enzyme from crude microbial lysate resulting in high yield and purity is reported. Significantly enhanced crystallization is enabled by...
Micropipette Aspiration‐Based Assessment of Single Channel Water Permeability
The method works at low reconstitution densities of water conducting channels and is not limited by unstirred layers. It allows for simultaneous measurements of channel...
Modeling the Residence Time Distribution of Integrated Continuous Bioprocesses
A thorough understanding of mass flows in the process is required by the Food and Drug Administration in their draft on guidelines for continuous integrated biomanufacturing. A...
Anything but Conventional Chromatography Approaches in Bioseparation
Anything but conventional chromatography is an increasingly relevant trend in downstream processing. These alternative approaches are put in perspective considering past...
Molecular Targets for the Testing of COVID‐19
RNA and proteins of a Betacoronavirus virion as well as virus induced antibodies can be used as molecular biomarkers for viral infection. This paper describes the principle of...
Generation Bio Leads a Trio of Biotech Companies Aiming for the Nasdaq
COVID-19 has ravaged the economy, and it was expected to quash the IPO market, too. But the biotech sector is defying the pandemic with crossover financings and freshly minted...
FDA Approves Evofem's “On-Demand” Non-Hormonal Birth Control Gel
While treatments for many health conditions have undergone reinvention in the past two decades, birth control options haven't changed much. On Friday, San Diego-based Evofem...
Past is prologue: Genetic 'memory' of ancestral environments helps organisms...
Organisms carry long-term 'memories' of their ancestral homelands that help them adapt to environmental change, according to a new study that involved raising chickens on the...