Production of trans-cinnamic acid by whole-cell bioconversion from l-phenylalanine in engineered Corynebacterium glutamicum
Trans-cinnamic acid is a phenylpropanoid with a broad spectrum of biological activities including antioxidant and antibacterial activities, and it also has high potential in...
1 hour ago - Microbial Cell Factories
A cell engineering approach to enzyme-based fed-batch fermentation
A fundamental problem associated with E. coli fermentations is the difficulty in achieving high cell densities in batch cultures, attributed in large part to the production and...
1 hour ago - Microbial Cell Factories
Buyer II - Inovio Pharmaceuticals - San Diego, CA
The Buyer II is a well-organized individual with excellent communication and interpersonal skills. This position interfaces primarily with the medical device...From Indeed...
6 hours ago - San Diego Biotechnology
Active constituents of Zanthoxylum nitidium from Yunnan Province against leukaemia cells in vitro
Zanthoxylum nitidium DC is well known for inhibiting the proliferation of human gastric, liver, kidney and lung cancer cells, though research on its potential use in treating...
9 hours ago - Chemistry Central
Biological knowledge-slanted random forest approach for the classification of calcified aortic valve stenosis
Calcific aortic valve stenosis is a fatal disease and there is no pharmacological treatment to prevent the progression of CAVS. This study aims to identify genes potentially...
13 hours ago - BioData Mining
Proteomic analysis revealed the roles of YRR1 deletion in enhancing the vanillin resistance of Saccharomyces cerevisiae
Vanillin is one of the important phenolic inhibitors in Saccharomyces cerevisiae for bioconversion of lignocellulosic materials and has been reported to inhibit the translation...
14 hours ago - Microbial Cell Factories
Design and heterologous expression of a novel dimeric LL37 variant in Pichia pastoris
The antimicrobial peptide LL37 is produced by white blood cells and various epithelial cells, and has the outstanding advantages of participating in immune regulation, causing...
14 hours ago - Microbial Cell Factories
The signaling role of extracellular ATP in co-culture of Shiraia sp. S9 and Pseudomonas fulva SB1 for enhancing hypocrellin A production
Adenosine 5′-triphosphate plays both a central role as an intracellular energy source, and a crucial extracellular signaling role in diverse physiological processes of animals...
14 hours ago - Microbial Cell Factories
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain
Nature Chemical Biology, Published online: 22 July 2021; doi:10.1038/s41589-021-00831-5 The full-length structure of HUWE1 reveals the bipartite organization of a giant E3...
14 hours ago - ACS Division of Biological Chemistry
Mapping the molecular basis for growth related phenotypes in industrial producer CHO cell lines using differential proteomic analysis
The ability to achieve high peak viable cell density earlier in CHO cell culture and maintain an extended cell viability throughout the production process is highly desirable...
18 hours ago - BMC Biotechnology
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Active constituents of Zanthoxylum nitidium from Yunnan Province against...
Zanthoxylum nitidium DC is well known for inhibiting the proliferation of human gastric, liver, kidney and lung cancer cells, though research on its potential use in treating...
Biological knowledge-slanted random forest approach for the classification...
Calcific aortic valve stenosis is a fatal disease and there is no pharmacological treatment to prevent the progression of CAVS. This study aims to identify genes potentially...
The signaling role of extracellular ATP in co-culture of Shiraia sp. S9 and...
Adenosine 5′-triphosphate plays both a central role as an intracellular energy source, and a crucial extracellular signaling role in diverse physiological processes of animals...
Design and heterologous expression of a novel dimeric LL37 variant in Pichia...
The antimicrobial peptide LL37 is produced by white blood cells and various epithelial cells, and has the outstanding advantages of participating in immune regulation, causing...
Proteomic analysis revealed the roles of YRR1 deletion in enhancing the...
Vanillin is one of the important phenolic inhibitors in Saccharomyces cerevisiae for bioconversion of lignocellulosic materials and has been reported to inhibit the translation...
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT...
Nature Chemical Biology, Published online: 22 July 2021; doi:10.1038/s41589-021-00831-5 The full-length structure of HUWE1 reveals the bipartite organization of a giant E3...
Mapping the molecular basis for growth related phenotypes in industrial...
The ability to achieve high peak viable cell density earlier in CHO cell culture and maintain an extended cell viability throughout the production process is highly desirable...
Senior Manager / Associate Director, Technical Operations Project Management...
Bachelor's Degree in Chemistry, Life Sciences, and/or Business with a minimum of 7 years' experience in the biotechnology/biopharmaceutical industry preferred. From Heron...
MegaLMM: Mega-scale linear mixed models for genomic predictions with...
Large-scale phenotype data can enhance the power of genomic prediction in plant and animal breeding, as well as human genetics. However, the statistical foundation of...
Circ 03955 promotes pancreatic cancer tumorigenesis and Warburg effect by...
Abstract Objectives Former studies found that circRNAs play an important part in the occurrence of a variety of malignant biological characteristics that are critical for...